Subgrouping of Type 2 Diabetes Mellitus Based on Proteinuria and Diabetic Control for Treatment and Follow-Up

Patients with type 2 diabetes mellitus (T2DM) exhibit improved symptoms at the start of treatment, but their conditions subsequently deteriorate after a few months treatment. In present study, patients treated glibenclamide and metformin were followed up for evaluation efficacy treatment based on some biochemical parameters in T2DM subgroups. The subgrouped according to glycated hemoglobin (HbA1c), sex, urinary albumin creatinine ratio (UACR), uric acid UA levels. A total 662 participated which aimed follow fasting blood sugar (FBS), (UA), UACR, lipid profiles beginning 4 months. Results showed that best effect occurred when classified UACR HbA1c. general, all parameters, especially profile levels, changed proteinuria compared those normal patients. Depending glycemic control subgroups, higher poor fair control, except HDLc, was lowest poor-control revealed significant improvement (p < 0.05) lipids, UA, HbA1c remained slightly increased measured by using subgroups better than obtained from whole group. who initially experienced tended ignore regular restricted diet, thereby worsening parameters.